A CU Cancer Center study published in the Dermatology Online Journal shows that YouTube also allows researchers, journals, and health advocates to connect directly with the public on topics of skin cancer and prevention.
Study Shows Tale of Two Prognoses in Pediatric Brain Tumor, Pilocytic Astrocytoma
June 2, 2014 · Comments Off
Research presented at the American Society for Clinical Oncology (ASCO) Annual Meeting 2014 used a newly designed test for "K:B gene fusion" to show that point mutations lead to a more dangerous form of the disease than does K:B fusion.
DREAM Project Crowdsources Answer to Cancer Cell Drug Sensitivities
June 2, 2014 · Comments Off
A study published June 1 in the journal Nature Biotechnology describes the results of an open challenge to predict which breast cancer cell lines will respond to which drugs, based only on the sum of cells’ genomic data. The winning entry, from the Helsinki Institute for Information Technology, was 78 percent accurate in identifying sensitive versus resistant cell lines, and was one of 44 algorithms submitted by groups from around the world.
Oncologists: How to Talk With Your Pathologist About Cancer Molecular Testing
June 1, 2014 · Comments Off
Aisner suggests close communication, systems approaches, keeping special requests to a minimum, and patience on the part of requesting oncologists. The key, she says, is writing new institutional protocols to keep pace with the new reliance on molecular testing.
ALK, ROS1 and now NTRK1: Study Shows Prevalence of New Genetic Driver in Lung Cancer
May 31, 2014 · Comments Off
Study reports the prevalence of the NTRK1 mutation in an unselected population of 450 lung cancer samples, with >1% percent of patients testing positive. This and other work from Dr. Doebele’s group forms the basis of a phase 1 clinical trial targeting NTRK1 mutations in advanced solid tumors (NCT02122913).
New University of Colorado study illuminates how cancer-killing gene may actually work
May 27, 2014 · Comments Off
Scientists armed with a supercomputer and a vast trove of newly collected data on the body’s most potent “tumor suppressor” gene have created the best map yet of how the gene works, an accomplishment that could lead to new techniques for fighting cancers, which are adept at disabling the gene in order to thrive.
Drug-Target Database Lets Researchers Match Old Drugs to New Uses
May 21, 2014 · Comments Off
There are thousands of drugs that silence many thousands of cancer-causing genetic abnormalities. Some of these drugs are in use now, but many of these drugs are sitting on shelves or could be used beyond the disease for which they were originally approved. Repurposing these drugs depends on matching drugs to targets.
Study Highlights New Drug, Molecular Insight into Triple Negative Breast Cancers
April 8, 2014 · Comments Off
AACR 2014 study showcases a new drug active against triple-negative breast cancer, and through analysis of the drug’s mechanism of action, offers increased understanding of the biology of this very aggressive form of breast cancer.
Gold nanorods attach to, kill bladder cancer cells
April 7, 2014 · Comments Off
Bladder cancer cells overexpress the protein EGFR; gold nanorods can be engineered to attach to EGFR proteins; and then the application of low-intensity laser to the tissue can preferentially heat these gold nanorods, killing the EGFR-rich cancer cells to which they are attached.
NTRK1: a new oncogene and target in lung cancer
April 7, 2014
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