Zombie Cancer Cells Eat Themselves to Live
April 5, 2014 · Comments Off
AACR 2014 study shows that the cellular process of autophagy in which cells "eat" parts of themselves in times of stress may allow cancer cells to recover and divide rather than die when faced with chemotherapies.
Study: Autophagy predicts which cancer cells live and die when faced with anti-cancer drugs
January 10, 2014 · Comments Off
When a tumor is treated with an anti-cancer drug, some cells die and, unfortunately, some cells tend to live. A University of Colorado Cancer Center study published in the journal Nature Cell Biology details a possible difference between the susceptible and resistant cells: the rate at which cells are able to cleanse themselves via the process known as autophagy.
AACR News: Autophagy-addicted breast cancers killed by anti-malaria drug, chloroquine
April 8, 2013 · Comments Off
The process of autophagy cleans cells – they wrap up the bad stuff and then dispose of it. And so it stands to reason that inhibiting autophagy would make cancer cells less able to cleanse themselves of chemotherapy and so more susceptible to the drugs. That's what the traditional anti-malaria drug, chloroquine, does – it inhibits autophagy. Existing clinical trials are testing chloroquine/chemotherapy combinations against breast cancer. Research presented at the AACR Annual Meeting 2013 shows that some breast cancer subtypes depend on autophagy more than others – and that inhibiting autophagy in breast cancers that depend on it may be enough alone to kill the disease.
Tightening the body’s cancer-catching net
November 30, 2012 · Comments Off
At CU Cancer Center, researchers, discover how dinosaurs, diabetes, Star Trek extras and Keith Richards combine to keep the body cancer-free.
Annual retreat shows the CU Cancer Center is greater than the sum of its parts
October 31, 2012 · Comments Off
At the annual CU Cancer Center retreat on October 30, Deputy Director Andrew Thorburn, PhD,...
Getting down to business
June 21, 2012 · Comments Off
Cancer Center Medical Director Tom Purcell brings corporate, medical experience By Todd Neff For a...
In my last glioblastoma grant application, I made the following statement: survival has barely moved...
Thorburn: Let’s blow our own trumpet more
November 3, 2011 · Comments Off
Last week, I visited the University of Pittsburgh Cancer Center to attend a couple of...
What I’m hoping for with these blogs is to stimulate debate about some of the...
NTRK1: a new oncogene and target in lung cancer
October 6, 2011
amc cancer fund American Association for Cancer Research andrew thorburn anthony elias antonio jimeno ASCO biomarkers bladder cancer breast cancer cancer cancer grants cancer research colorado cancer stem cells Cancer Survivorship clinical trial colorado cancer benefit colorectal cancer crizotinib CU Cancer Center Dan Theodorescu fred hirsch funding opportunity grant head-and-neck cancer james degregori jennifer richer leukemia lung cancer lung cancer research melanoma microRNA ovarian cancer Pancreatic cancer paul bunn prostate cancer publications rajesh agarwal ross camidge skin cancer Thomas Flaig tim byers university of colorado cancer center university of colorado hospital university of colorado school of medicine wells messersmith
Dinner in white is tomorrow night! You will not want to miss out on this event! Purchase your tickets now! fb.me/3GI6wCQf6
Who is participating in the Cancer League of Colorado's Race for Research this weekend? We'll have a team there... fb.me/6He65NwH3
I posted 20 photos on Facebook in the album "CU Cancer Center Poster Session 2014" fb.me/1f4s7nyfW