AACR News: Autophagy-addicted breast cancers killed by anti-malaria drug, chloroquine
April 8, 2013 · Comments Off
The process of autophagy cleans cells – they wrap up the bad stuff and then dispose of it. And so it stands to reason that inhibiting autophagy would make cancer cells less able to cleanse themselves of chemotherapy and so more susceptible to the drugs. That's what the traditional anti-malaria drug, chloroquine, does – it inhibits autophagy. Existing clinical trials are testing chloroquine/chemotherapy combinations against breast cancer. Research presented at the AACR Annual Meeting 2013 shows that some breast cancer subtypes depend on autophagy more than others – and that inhibiting autophagy in breast cancers that depend on it may be enough alone to kill the disease.
Tightening the body’s cancer-catching net
November 30, 2012 · Comments Off
At CU Cancer Center, researchers, discover how dinosaurs, diabetes, Star Trek extras and Keith Richards combine to keep the body cancer-free.
Annual retreat shows the CU Cancer Center is greater than the sum of its parts
October 31, 2012 · Comments Off
At the annual CU Cancer Center retreat on October 30, Deputy Director Andrew Thorburn, PhD,...
Getting down to business
June 21, 2012 · Comments Off
Cancer Center Medical Director Tom Purcell brings corporate, medical experience By Todd Neff For a...
In my last glioblastoma grant application, I made the following statement: survival has barely moved...
Thorburn: Let’s blow our own trumpet more
November 3, 2011 · Comments Off
Last week, I visited the University of Pittsburgh Cancer Center to attend a couple of...
What I’m hoping for with these blogs is to stimulate debate about some of the...
Cancer League of Colorado commits $2 million toward CU Cancer Center endowed chair
September 13, 2011 · Comments Off
Andrew Thorburn nears the end of his rappel off One Denver Place on Aug. 27,...
Thorburn: Better treatment for cancer start by ending “sloppy science”
September 8, 2011 · Comments Off
Dr. Andrew Thorburn is deputy director of the University of Colorado Cancer Center and chair...
NTRK1: a new oncogene and target in lung cancer
September 8, 2011
A diet of resistant starch helps the body resist colorectal cancer
September 8, 2011
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Today is the day! Enjoy some blueberry pancakes and dress in all blue for Dress in Blue day to increase... http://t.co/LnYh9iT1lW
One last reminder. Wear blue tomorrow for Dress in Blue Day! http://t.co/dNKEDueKNv
In Health Care, Choice Is Overrated. We're glad our patient got the second opinion needed. Hope others can too. http://t.co/3T9CrAj8E2
President Obama has declared March National Colorectal Cancer Awareness Month! Remember to wear blue this Friday... http://t.co/neqgyKCzAC