Study: Autophagy predicts which cancer cells live and die when faced with anti-cancer drugs
January 10, 2014 · Comments Off
When a tumor is treated with an anti-cancer drug, some cells die and, unfortunately, some cells tend to live. A University of Colorado Cancer Center study published in the journal Nature Cell Biology details a possible difference between the susceptible and resistant cells: the rate at which cells are able to cleanse themselves via the process known as autophagy.
AACR News: Autophagy-addicted breast cancers killed by anti-malaria drug, chloroquine
April 8, 2013 · Comments Off
The process of autophagy cleans cells – they wrap up the bad stuff and then dispose of it. And so it stands to reason that inhibiting autophagy would make cancer cells less able to cleanse themselves of chemotherapy and so more susceptible to the drugs. That's what the traditional anti-malaria drug, chloroquine, does – it inhibits autophagy. Existing clinical trials are testing chloroquine/chemotherapy combinations against breast cancer. Research presented at the AACR Annual Meeting 2013 shows that some breast cancer subtypes depend on autophagy more than others – and that inhibiting autophagy in breast cancers that depend on it may be enough alone to kill the disease.
Tightening the body’s cancer-catching net
November 30, 2012 · Comments Off
At CU Cancer Center, researchers, discover how dinosaurs, diabetes, Star Trek extras and Keith Richards combine to keep the body cancer-free.
Annual retreat shows the CU Cancer Center is greater than the sum of its parts
October 31, 2012 · Comments Off
At the annual CU Cancer Center retreat on October 30, Deputy Director Andrew Thorburn, PhD,...
Getting down to business
June 21, 2012 · Comments Off
Cancer Center Medical Director Tom Purcell brings corporate, medical experience By Todd Neff For a...
In my last glioblastoma grant application, I made the following statement: survival has barely moved...
Thorburn: Let’s blow our own trumpet more
November 3, 2011 · Comments Off
Last week, I visited the University of Pittsburgh Cancer Center to attend a couple of...
What I’m hoping for with these blogs is to stimulate debate about some of the...
Cancer League of Colorado commits $2 million toward CU Cancer Center endowed chair
September 13, 2011 · Comments Off
Andrew Thorburn nears the end of his rappel off One Denver Place on Aug. 27,...
New book chronicles wife’s cancer journey, provides therapeutic value
September 13, 2011
Bitter melon juice prevents pancreatic cancer in mouse models
September 13, 2011
NTRK1: a new oncogene and target in lung cancer
September 13, 2011
Gold nanorods attach to, kill bladder cancer cells
April 7, 2014 · No comments
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It's time to Love Your Bottom! Please join our colorectal cancer experts at the Lone Tree Health Center for a... http://t.co/jn8VBzzysw
Thanks to The Denver Post for covering our Cocktails for a Cure event last week and thanks to 400 women who... http://t.co/vHZoiTAea0
3D technology in mammograms another tool in breast cancer fight http://t.co/t8g9aSdYPT
The latest mammography technology is on wheels! Yep, the Pink Life Saver is now providing 3D mammogram technology... http://t.co/Vx0eDiuce3
Oh What a Night! Watch the video from "Cocktails for a Cure" if you have a couple minutes. The event was a... http://t.co/oAWSiHrKWi