National Clinical Trial Tests Power of COXEN Model to Predict Best Treatment for Bladder Cancer
August 13, 2014 · Comments Off
COXEN, a computer model that suggests treatment based on cancer genetics, is being tested in a new clinical trial, here at the CU Cancer Center and nationally via clinical sites of the Southwest Oncology Research Group.
“Treatments Waiting to be Discovered” Inside New Database
August 5, 2014 · Comments Off
University of Colorado Cancer Center database, multiMiR, allows researchers to search microRNA, gene, disease, and drug interactions.
Gold nanorods attach to, kill bladder cancer cells
April 7, 2014 · Comments Off
Bladder cancer cells overexpress the protein EGFR; gold nanorods can be engineered to attach to EGFR proteins; and then the application of low-intensity laser to the tissue can preferentially heat these gold nanorods, killing the EGFR-rich cancer cells to which they are attached.
Major Genetic Study Links Liver Disease Gene to Bladder Cancer
April 4, 2014 · Comments Off
A University of Colorado Cancer Center study published today in Journal of the National Cancer Institute (with related research being presented tomorrow at the American Association for Cancer Research Annual Conference 2014) details the discovery of a new genetic driver of bladder cancer: silencing of the gene AGL.
Lung and bladder cancers have common cell-cycle biomarkers
January 29, 2014 · Comments Off
CU Cancer Center study: bladder and lung cancers are marked by shared differences in the genetics that control the cell cycle.
Different parents, different children: Muscle-invasive and non-muscle invasive bladder cancers arise from different stem cells
December 17, 2013 · Comments Off
A CU Cancer Center study published today in the journal Stem Cells shows that progenitor cells that create dangerous, muscle-invasive bladder cancer are different than the progenitor cells that create non-muscle invasive bladder cancer. Though these two cancers grow at the same site, they are different diseases.
AACR News: Little molecule makes big difference in bladder cancer metastasis
April 9, 2013 · Comments Off
In order to kill, bladder cancer must metastasize, most commonly to the lung – what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University of Colorado Cancer Center at the AACR Annual Meeting 2013 shows that one big difference is a little molecule known as hsa-miR-146a.
AACR News: Misregulated genes common to tobacco-related cancers offer potential new prognostic tool
April 9, 2013 · Comments Off
"We ultimately envision this as a prognostic tool to predict survival rates for people with tobacco related cancers. Recognizing patients with high expression of these genes could help us predict risk and so match patients with the most appropriate treatments," says Garrett Dancik, PhD, postdoc in the lab of Dan Theodorescu, MD, PhD, director of the University of Colorado Cancer Center.
Body’s ibuprofen, SPARC, reduces inflammation and thus bladder cancer development and metastasis
January 16, 2013 · Comments Off
A University of Colorado Cancer Center study published today in the Journal of Clinical Investigation shows that the protein SPARC (Secreted Protein Acidic and Rich in Cysteine) acts much like an anti-inflammatory drug, attempting to heal tissues inflamed by tumors. Likewise, cancers – for example, bladder cancer in this study – have developed ways to turn off the production of SPARC, thus allowing growth and metastasis, especially to the lung where bladder cancer is frequently fatal.
Bitter melon juice prevents pancreatic cancer in mouse models
January 16, 2013
NTRK1: a new oncogene and target in lung cancer
January 16, 2013
NEJM: Crizotinib Effective in Phase 1 Trial Against ROS1 Lung Cancer
September 30, 2014 · No comments
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