Study Pinpoints How RhoGDI2 Suppresses Bladder Cancer Metastasis
February 12, 2015 · Comments Off
Discovery that RhoGDI2 blocks action of RhoC to suppress tumors may finally provide a druggable target allowing researchers to manipulate this signaling in a way that reduces tumor metastasis.
New Knowledge of Genes Driving Bladder Cancer Points to Targeted Treatments
September 15, 2014 · Comments Off
A collaborative study between researchers at the University of Colorado Cancer Center and the National Cancer Institute (NCI) published today in the journal Clinical Cancer Research takes an important step toward defining the genetics of bladder cancer, and implies there may be at least two distinct genetic types of the disease.
National Clinical Trial Tests Power of COXEN Model to Predict Best Treatment for Bladder Cancer
August 13, 2014 · Comments Off
COXEN, a computer model that suggests treatment based on cancer genetics, is being tested in a new clinical trial, here at the CU Cancer Center and nationally via clinical sites of the Southwest Oncology Research Group.
“Treatments Waiting to be Discovered” Inside New Database
August 5, 2014 · Comments Off
University of Colorado Cancer Center database, multiMiR, allows researchers to search microRNA, gene, disease, and drug interactions.
Gold nanorods attach to, kill bladder cancer cells
April 7, 2014 · Comments Off
Bladder cancer cells overexpress the protein EGFR; gold nanorods can be engineered to attach to EGFR proteins; and then the application of low-intensity laser to the tissue can preferentially heat these gold nanorods, killing the EGFR-rich cancer cells to which they are attached.
Major Genetic Study Links Liver Disease Gene to Bladder Cancer
April 4, 2014 · Comments Off
A University of Colorado Cancer Center study published today in Journal of the National Cancer Institute (with related research being presented tomorrow at the American Association for Cancer Research Annual Conference 2014) details the discovery of a new genetic driver of bladder cancer: silencing of the gene AGL.
Lung and bladder cancers have common cell-cycle biomarkers
January 29, 2014 · Comments Off
CU Cancer Center study: bladder and lung cancers are marked by shared differences in the genetics that control the cell cycle.
Different parents, different children: Muscle-invasive and non-muscle invasive bladder cancers arise from different stem cells
December 17, 2013 · Comments Off
A CU Cancer Center study published today in the journal Stem Cells shows that progenitor cells that create dangerous, muscle-invasive bladder cancer are different than the progenitor cells that create non-muscle invasive bladder cancer. Though these two cancers grow at the same site, they are different diseases.
AACR News: Little molecule makes big difference in bladder cancer metastasis
April 9, 2013 · Comments Off
In order to kill, bladder cancer must metastasize, most commonly to the lung – what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University of Colorado Cancer Center at the AACR Annual Meeting 2013 shows that one big difference is a little molecule known as hsa-miR-146a.
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