All posts tagged crizotinib

  • Dandelion

    “Weeding the garden” with radiation allows ALK+ lung cancer patients to continue crizotinib, increasing survival

    CU Cancer Center study shows that patients taking crizotinib for ALK+ non-small cell lung cancer may safely and durably use up to three courses of targeted radiation therapy to eradicate pockets of drug-resistant disease. Eliminating these pockets of resistant disease allows patients to continue treating the overall condition with crizotinib, leading to improved 2-year survival rate compared with patients forced to discontinue the drug sooner.

Colorectal cancer cells like these may develop from some of the same gene alterations found in subsets of lung cancer
Flickr: Sara | B.
A chromosomal translocation is the exchange of genetic material between chromosomes. Some translocations cause cancer. And some translocations are targets for emerging, personalized therapies.