All posts tagged james degregori

  • Math

    Mutations Need Help From Aging Tissue to Cause Leukemia

    “We had been looking inside cells for the causes of cancer, but that wasn’t enough. There was something happening outside the cells that mattered,” says James DeGregori, PhD.

Molecularly targeted therapies hold promise for many pediatric cancers, but at what cost? Image: Flickr/Cliff1066
Cancer-Catching Net
Changing tissue landscape and not necessarily accumulated oncogenic mutations drives higher cancer rates in the elderly. Image: Mick Jagger, cc license.
James DeGregori, Team In Training
Chemotherapy pushes AML cancer cells toward a corner -- the protein WEE1 helps them brake to stay on track. Take away WEE1 and AML cells hit the wall. (Photo courtesy of Flickr user ShinyThings, cc license.)
Cancer cells are like prarie dogs -- when a first-line cancer drug plugs the front dooor, cancer cells evolve to find other escapes. Photo courtesy of Flickr user gripso_banana_prune, CC license.
DeGregori
DeGregori